WWTR1 Produits
(WW Domain Containing Transcription Regulator 1 (WWTR1))
Catégories
This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010].
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Catégories WWTR1 en vedette
WWTR1 Anticorps
High quality antibodies with extensive validation data.
WWTR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
WWTR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN6150278
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Human, Mouse, Rabbit, Rat
Application
WB
Validations
- (5)
N° du produit
ABIN2779708
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (3)
N° du produit
ABIN525503
Quantité
100 μg
Fiche technique
Fiche technique
WWTR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325410
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325412
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN2132584
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits WWTR1
: "TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression." dans: Nature communications, Vol. 10, Issue 1, pp. 421, (2019) (PubMed).: "Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis." dans: Cancer cell, Vol. 33, Issue 2, pp. 292-308.e7, (2018) (PubMed).
: "PGC-1α Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ." dans: Cell stem cell, Vol. 23, Issue 2, pp. 193-209.e5, (2018) (PubMed).
: "Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a β1-integrin-FAK-YAP1/TAZ signaling pathway." dans: NPJ precision oncology, Vol. 2, Issue 1, pp. 2, (2018) (PubMed).
: "Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion." dans: Cell systems, Vol. 4, Issue 1, pp. 84-96.e6, (2017) (PubMed).
: "A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination." dans: Nature communications, Vol. 8, pp. 15161, (2017) (PubMed).
: "Lentivirus-TAZ Administration Alleviates Osteoporotic Phenotypes in the Femoral Neck of Ovariectomized Rats." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 38, Issue 1, pp. 283-94, (2016) (PubMed).
: "Role of the YAP Oncoprotein in Priming Ras-Driven Rhabdomyosarcoma." dans: PLoS ONE, Vol. 10, Issue 10, pp. e0140781, (2015) (PubMed).
: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." dans: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).
: "HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells." dans: Oncotarget, Vol. 6, Issue 14, pp. 11768-78, (2015) (PubMed).
Synonymes et noms alternatifs relatifs à WWTR1
WW domain containing transcription regulator 1 L homeolog (wwtr1.L), WW domain containing transcription regulator 1 (wwtr1), WW domain containing transcription regulator 1 (WWTR1), WW domain containing transcription regulator 1 (Wwtr1), 2310058J06Rik, 2610021I22Rik, C78399, TAZ, Taz, WWTR1Protein level used designations for WWTR1
- WW domain containing transcription regulator 1
- WW domain-containing transcription regulator protein 1
- taz
- WW domain-containing transcription regulator protein 1-like
- transcriptional co-activator with PDZ-binding motif
- transcriptional coactivator with PDZ-binding motif
- transcriptional coactivator with PDZ binding motif
- transcriptional co-activator with PDZ-binding motif (TA)Z
- transcriptional co-activator with PDZ-binding motif (TAZ)
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