XRCC4 Produits
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 (XRCC4))
Catégories
The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq, Sep 2008].
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Catégories XRCC4 en vedette
XRCC4 Anticorps
High quality antibodies with extensive validation data.
XRCC4 Kits ELISA
Reliable ELISA kits for a wide range of species.
XRCC4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
XRCC4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (2)
- (7)
N° du produit
ABIN3022382
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (1)
- (5)
N° du produit
ABIN1327721
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (4)
N° du produit
ABIN7259376
Quantité
200 μL
Fiche technique
Fiche technique
XRCC4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1381600
Quantité
96 tests
Fiche technique
Fiche technique
XRCC4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325469
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325471
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
N° du produit
ABIN2735698
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits XRCC4
: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." dans: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." dans: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).
: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." dans: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining." dans: Nucleic acids research, Vol. 45, Issue 18, pp. 10583-10594, (2017) (PubMed).
: "A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage." dans: Genes & development, Vol. 29, Issue 11, pp. 1151-63, (2015) (PubMed).
: "Organization and dynamics of the nonhomologous end-joining machinery during DNA double-strand break repair." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 20, pp. E2575-84, (2015) (PubMed).
: "A stress-induced cellular aging model with postnatal neural stem cells." dans: Cell death & disease, Vol. 5, pp. e1116, (2014) (PubMed).
: "Quantification of XRCC and DNA-PK proteins in cancer cell lines and human tumors by LC-MS/MS." dans: Bioanalysis, Vol. 6, Issue 22, pp. 2969-83, (2014) (PubMed).
: "A regulatory role for the cohesin loader NIPBL in nonhomologous end joining during immunoglobulin class switch recombination." dans: The Journal of experimental medicine, Vol. 210, Issue 12, pp. 2503-13, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à XRCC4
X-ray repair cross complementing 4 (XRCC4), X-ray repair complementing defective repair in Chinese hamster cells 4 (xrcc4), X-ray repair complementing defective repair in Chinese hamster cells 4 L homeolog (xrcc4.L), DNA ligase IV-binding protein (XRCC4), X-ray repair complementing defective repair in Chinese hamster cells 4 (Xrcc4), X-ray repair cross complementing 4 (Xrcc4), 2310057B22Rik, AW413319, AW545101, homolog of human DNA ligase iv-binding protein XRCC4, MGC81443, zgc:73312Protein level used designations for XRCC4
- DNA repair protein XRCC4
- X-ray repair complementing defective repair in Chinese hamster cells 4
- DNA-repair protein XRCC4
- X-ray repair cross complementing protein 4
- X-ray repair cross-complementing protein 4
- X-ray repair, complementing defective, repair in Chinese hamster
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