XRCC5 Produits
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Catégories
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008].
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Catégories XRCC5 en vedette
XRCC5 Anticorps
High quality antibodies with extensive validation data.
XRCC5 Kits ELISA
Reliable ELISA kits for a wide range of species.
XRCC5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
XRCC5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IP
Validations
- (2)
- (12)
N° du produit
ABIN6150309
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (3)
- (6)
N° du produit
ABIN563391
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, FACS, ICC
Validations
- (2)
- (5)
N° du produit
ABIN969463
Quantité
100 μL
Fiche technique
Fiche technique
XRCC5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971209
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960572
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960573
Quantité
96 tests
Fiche technique
Fiche technique
XRCC5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1325473
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN5710636
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits XRCC5
: "Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment." dans: Asian Pacific journal of cancer prevention : APJCP, Vol. 20, Issue 12, pp. 3679-3687, (2020) (PubMed).: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." dans: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).
: "BCL2-overexpressing prostate cancer cells rely on PARP1-dependent end-joining and are sensitive to combined PARP inhibitor and radiation therapy." dans: Cancer letters, Vol. 423, pp. 60-70, (2018) (PubMed).
: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).
: "Influence of XRCC4 expression in esophageal cancer cells on the response to radiotherapy." dans: Medical molecular morphology, Vol. 50, Issue 1, pp. 25-33, (2016) (PubMed).
: "Expression of Ku70 predicts results of radiotherapy in prostate cancer." dans: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], Vol. 193, Issue 1, pp. 29-37, (2016) (PubMed).
: "Dual functions of the homeoprotein DLX4 in modulating responsiveness of tumor cells to topoisomerase II-targeting drugs." dans: Cancer research, Vol. 73, Issue 2, pp. 1000-10, (2013) (PubMed).
: "Serum anti-Ku86 is a potential biomarker for early detection of hepatitis C virus-related hepatocellular carcinoma." dans: Biochemical and biophysical research communications, Vol. 421, Issue 4, pp. 837-43, (2012) (PubMed).
: "Ku proteins interact with activator protein-2 transcription factors and contribute to ERBB2 overexpression in breast cancer cell lines." dans: Breast cancer research : BCR, Vol. 11, Issue 6, pp. R83, (2010) (PubMed).
: "The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A." dans: BMC medicine, Vol. 8, pp. 19, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à XRCC5
X-ray repair cross complementing 5 (XRCC5), X-ray repair complementing defective repair in Chinese hamster cells 5 (Xrcc5), X-ray repair cross complementing 5 (Xrcc5), X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog (xrcc5.L), AI314015, KARP-1, KARP1, Ku80, KU80, Ku86, KUB2, Kup80, NFIV, XRCC5, xrcc5-aProtein level used designations for XRCC5
- Ku autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa)
- X-ray repair protein
- X-ray repair cross-complementing protein 5
- X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
- ATP-dependent DNA helicase II
- ATP-dependent DNA helicase 2 subunit 2-like
- x-ray repair cross-complementing protein 5-like
- ATP-dependent DNA helicase 2 subunit 2
- ATP-dependent DNA helicase II 80 kDa subunit
- CTC box-binding factor 85 kDa subunit
- CTC85
- CTCBF
- DNA repair protein XRCC5
- Ku p80
- ku autoantigen protein p86 homolog
- nuclear factor IV
- Ku autoantigen, 80kD)
- X-ray repair cross complementation (double-strand-break rejoining
- X-ray repair cross complementation (double-strand-break rejoining; Ku autoantigen, 80kD)
- 86 kDa subunit of Ku antigen
- Ku autoantigen, 80kDa
- Ku86 autoantigen related protein 1
- TLAA
- lupus Ku autoantigen protein p86
- thyroid-lupus autoantigen
- X-ray repair complementing defective repair in Chinese hamster cells 5
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