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XRCC6 Produits

(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 6 (XRCC6))

Catégories

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008].

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Catégories XRCC6 en vedette

XRCC6 Anticorps

High quality antibodies with extensive validation data.

XRCC6 Kits ELISA

Reliable ELISA kits for a wide range of species.

XRCC6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

XRCC6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, IHC (p)
Validations
  • (2)
  • (6)
N° du produit ABIN560973
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, IHC (p), IP, ICC, PLA
Validations
  • (1)
  • (6)
N° du produit ABIN2855186
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (18)
N° du produit ABIN1513143
Quantité 100 μg
Fiche technique Fiche technique

XRCC6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6960574
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6960575
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381279
Quantité 96 tests
Fiche technique Fiche technique

XRCC6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1325475
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7390070
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7390073
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits XRCC6

Loshchenova, Sergeeva, Limonov, Guo, Dianov: "Sp1-independent downregulation of NHEJ in response to BER deficiency." dans: DNA repair, Vol. 86, pp. 102740, (2020) (PubMed).

Rehman, Vijayakumar, Jaiswal, Jain, Mukherjee, Vellarikkal, Dieffenbach, Fredenburgh, Prakash, Ghosh, Agrawal, Mabalirajan: "Noncanonical role for Ku70/80 in the prevention of allergic airway inflammation via maintenance of airway epithelial cell organelle homeostasis." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 319, Issue 4, pp. L728-L741, (2020) (PubMed).

Garcia-Moreno, Noerenberg, Ni, Järvelin, González-Almela, Lenz, Bach-Pages, Cox, Avolio, Davis, Hester, Sohier, Li, Heikel, Michlewski, Sanz, Carrasco, Ricci, Pelechano, Davis, Fischer, Mohammed et al.: "System-wide Profiling of RNA-Binding Proteins Uncovers Key Regulators of Virus Infection. ..." dans: Molecular cell, (2019) (PubMed).

Wang, Lai, Guo, Peng, Liu, Hong, Wei, Li, Jiang, Wang, Li, Lei, Zhao, Xu: "Inhibition of Ku70 in a high-glucose environment aggravates bupivacaine-induced dorsal root ganglion neurotoxicity." dans: Toxicology letters, Vol. 318, pp. 104-113, (2019) (PubMed).

Zhang, Chang, Sun, Chen, Yang, Tang, Jing, Kang, He, Wu, Wei, Wang, Xu, Zhu, Shen, Zeng, Wang, Liu, Zhang, Mao, Jiang, Sun: "Histone H3K27 methylation modulates the dynamics of FANCD2 on chromatin to facilitate NHEJ and genome stability." dans: Journal of cell science, Vol. 131, Issue 12, (2018) (PubMed).

Chakraborty, Tapryal, Venkova, Horikoshi, Pandita, Sarker, Sarkar, Pandita, Hazra: "Classical non-homologous end-joining pathway utilizes nascent RNA for error-free double-strand break repair of transcribed genes." dans: Nature communications, Vol. 7, pp. 13049, (2018) (PubMed).

Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." dans: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

Yoon, Stadler, Beermann, Schmidt, Windelborn, Schneiderat, Wright, Miller: "Immortalized myogenic cells from congenital muscular dystrophy type1A patients recapitulate aberrant caspase activation in pathogenesis: a new tool for MDC1A research." dans: Skeletal muscle, Vol. 3, Issue 1, pp. 28, (2014) (PubMed).

Yang, Fuller, Morgan, Shibata, McDonnell, Clyne, Young: "Use of phage display to identify novel mineralocorticoid receptor-interacting proteins." dans: Molecular endocrinology (Baltimore, Md.), Vol. 28, Issue 9, pp. 1571-84, (2014) (PubMed).

Ishida, Akita, Mori, Tanida, Toda, Inoue, Nakada: "Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33." dans: The Journal of biological chemistry, Vol. 289, Issue 36, pp. 25341-50, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à XRCC6

X-ray repair cross complementing 6 (XRCC6), ATP-dependent DNA helicase II, 70 kDa subunit (Bm1_41430), X-ray repair complementing defective repair in Chinese hamster cells 6 L homeolog (xrcc6.L), X-ray repair complementing defective repair in Chinese hamster cells 6 (Xrcc6), X-ray repair cross complementing 6 (Xrcc6), X-ray repair complementing defective repair in Chinese hamster cells 6 (XRCC6), 70kDa, CTC75, CTCBF, G22P1, G22p1, KU70, Ku70, Kup70, ML8, TLAA

Protein level used designations for XRCC6

  • ATP-dependent DNA helicase 2 subunit 1
  • ATP-dependent DNA helicase II, 70 kDa subunit
  • X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa)
  • X-ray repair cross-complementing protein 6
  • 5'-dRP lyase Ku70
  • 5'-deoxyribose-5-phosphate lyase Ku70
  • 70 kDa subunit of Ku antigen
  • ATP-dependent DNA helicase II 70 kDa subunit
  • CTC box binding factor 75 kDa subunit
  • CTC box-binding factor 75 kDa subunit
  • DNA repair protein XRCC6
  • Ku autoantigen p70 subunit
  • Ku autoantigen, 70kDa
  • lupus Ku autoantigen protein p70
  • thyroid autoantigen 70kD (Ku antigen)
  • thyroid autoantigen 70kDa (Ku antigen)
  • thyroid-lupus autoantigen p70
  • 5'-dRP/AP lyase Ku70
  • CTC75
  • CTCBF
  • Ku p70
  • ku autoantigen protein p70 homolog
  • thyroid autoantigen 70 kDa
  • Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa)
  • thyroid autoantigen
  • X-ray repair cross-complementing protein 5
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