ZYX Produits
(Zyxin (ZYX))
Catégories
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].
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Catégories ZYX en vedette
ZYX Anticorps
High quality antibodies with extensive validation data.
ZYX Kits ELISA
Reliable ELISA kits for a wide range of species.
ZYX Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ZYX recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IP, RNAi
Validations
- (2)
- (6)
N° du produit
ABIN563471
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (1)
- (4)
N° du produit
ABIN521634
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
N° du produit
ABIN6266149
Quantité
100 μL
Fiche technique
Fiche technique
ZYX recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975027
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960598
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1168973
Quantité
96 tests
Fiche technique
Fiche technique
ZYX recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125821
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1326572
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7396079
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits ZYX
: "Substrate engagement of integrins α5β1 and αvβ3 is necessary, but not sufficient, for high directional persistence in migration on fibronectin." dans: Scientific reports, Vol. 6, pp. 23258, (2016) (PubMed).: "NBR1 enables autophagy-dependent focal adhesion turnover." dans: The Journal of cell biology, Vol. 212, Issue 5, pp. 577-90, (2016) (PubMed).
: "α-Actinin-4 enhances colorectal cancer cell invasion by suppressing focal adhesion maturation." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0120616, (2015) (PubMed).
: "Cell shape-dependent early responses of fibroblasts to cyclic strain." dans: Biochimica et biophysica acta, Vol. 1833, Issue 12, pp. 3415-25, (2013) (PubMed).
: "Zyxin is a transforming growth factor-? (TGF-?)/Smad3 target gene that regulates lung cancer cell motility via integrin ?5?1." dans: The Journal of biological chemistry, Vol. 287, Issue 37, pp. 31393-405, (2012) (PubMed).
: "Cell-penetrating peptides with intracellular actin-remodeling activity in malignant fibroblasts." dans: The Journal of biological chemistry, Vol. 285, Issue 10, pp. 7712-21, (2010) (PubMed).
: "Domain analysis of alpha-actinin reveals new aspects of its association with F-actin during cytokinesis." dans: Experimental cell research, Vol. 316, Issue 12, pp. 1925-34, (2010) (PubMed).
: "Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis." dans: Molecular biology of the cell, Vol. 20, Issue 13, pp. 3115-24, (2009) (PubMed).
: "mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes." dans: American journal of physiology. Renal physiology, Vol. 296, Issue 2, pp. F418-26, (2009) (PubMed).
: "Targeted disruption of the mouse Lipoma Preferred Partner gene." dans: Biochemical and biophysical research communications, Vol. 379, Issue 2, pp. 368-73, (2009) (PubMed).
Synonymes et noms alternatifs relatifs à ZYX
Zyxin (zyx-1), Zyxin (Zyx), zyxin (zyx), zyxin (ZYX), zyxin (EDI_201420), zyxin (Zyx), zyxin S homeolog (zyx.S), 9530098H06Rik, BcDNA:LD06023, CG32018, DLim-1, Dmel\\CG32018, DmLIM-1, ESP-2, HED-2, lim, Lim102EF, MGC145270, R75157, zgc:171680, ZYX, zyx, ZYX102, Zyx102, zyx102, Zyx102EF, zyxinProtein level used designations for ZYX
- ZYXin family member (zyx-1)
- CG32018-PA
- CG32018-PB
- CG32018-PG
- CG32018-PH
- Zyx-PA
- Zyx-PB
- Zyx-PG
- Zyx-PH
- Zyx102EF
- zyxin
- hypothetical protein LOC779718
- zyxin-2
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